The clinical effects of hospitalization in a low pollutant room on atopic dermatitis
نویسندگان
چکیده
BACKGROUND Environmental pollutants are thought to be one of major triggers of atopic dermatitis (AD). OBJECTIVE We attempted to evaluate the clinical effects of environment with low indoor pollutant levels on AD management. METHODS Fifty-one children (mean age 1.7 years) with moderate to severe AD who failed to show improvement with conventional management were recruited. Disease severity was assessed by SCORAD (Scoring of AD) indices. They were admitted in a low pollutant oom for 3-4 days (mean 3.3 days) which was designed to keep low levels of dust, house dust mites, micro-organisms, and indoor air pollutants such as total volatile organic compounds (TVOCs), particulate matter (PM), and so on. Air pollutant levels in the low pollutant room were lower than primary standards defined by the Korean Ministry of Environment. we compared disease severity on admission and after discharge, and the pollutant levels of each patient's home and low pollutant room. RESULTS The SCORAD was significantly reduced from 42.0 ± 11 .5 to 29.8 ± 8.9 (p < 0.001) by management in a low pollutant room. PM(2.5), PM(10), formaldehyde, TVOCs, carbon dioxide, bacterial suspensions, and indoor molds were significantly higher in the patient's home than low pollutant room. Out of 29 patients who deteriorated after discharge to their home, 8 patients were admitted again, and their SCORAD was rapidly decreased from 53.1 ± 16.2 to 39.2 ± 9.8 (p = 0.036). CONCLUSION Indoor air pollutants are likely to affect AD in susceptible individuals. Environmental control to lower indoor air pollutant levels might be necessary for better management of AD in some patients.
منابع مشابه
A comparison of effects on healing and recurrence from Atopic dermatitis Borage tea vs. corton
Background: Atopic dermatitis is a hereditary, chronic and recurrent disease (in 5%-10% of children).Topical corton is prescribed for this lesion as a routine cure. Studies show that patients with atopic dermatitis suffer from Essential fatty acids (EFA) deficiency. Borage tea is one of the sources enriched of EFA, it is a self – growing plant which is found abundantly in Iran. This clinica...
متن کاملCutaneous Leishmaniasis in Atopic Dermatitis Patients in Comparison with the Control Group in Kerman
Background: Atopic dermatitis is the most common chronic inflammatory dermatitis, due to immunological disorders. Patients with atopic dermatitis are prone to infectious diseases including bacterial infections. On the other hand, atopy may be protective against helminthes parasites. The objective of this study was to compare the frequency and clinical presentations of cutaneous leishmaniasis in...
متن کاملTreatment of Atopic Dermatitis (Jarab) in a 38-year-old Female Patient with Traditional Medicine at Tehran University of Medical Sciences in 2015
Abstract Background: Atopic dermatitis is a common skin disease associated with chronic inflammation in the skin and itches and most patients have a positive family history of dermatitis. The major treatment of dermatitis, based on allopathic medicine, includes symptomatic treatment by oral antihistamines and topical or oral corticosteroids, which, in lo...
متن کاملA short review on immunology of Atopic dermatitis
Atopic dermatitis (AD) is a pruritic, relapsing, chronic disease that arises most commonly during infancy, childhood, or adolescence. It is clear that genetic factors are important in AD, a family history of AD, allergic rhinitis, and/or asthma and other “Atopic” phenomena being common in patient with AD. The two main pathogenetic characteristic of AD are: I) IgE-mediated antigen dependent “Spe...
متن کاملCanine atopic/allergic dermatitis in Mashhad (North-East of Iran): clinical observations
The aim of this study was to elucidate the prevalence of canine atopic/allergic dermatitis in Mashhad (North-East of Iran) in a hospital-population of dogs and to evaluate its clinical features according to the diagnostic criteria of the disease by Willemse and Prélaud. Among 111 canine patients with dermatologic problems, admitted to Ferdowsi University of Mashhad, Veterinary Teaching Hospital...
متن کامل